Forget GLP-1 drugs like Ozempic and Wegovy: Wistar researchers say a single DNA-based injection produced weight loss an…
By Chubby♨️ · Research
Forget GLP-1 drugs like Ozempic and Wegovy: Wistar researchers say a single DNA-based injection produced weight loss and blood glucose control in mouse models for up to 10x longer. The method uses plasmid DNA plus electroporation to give cells instructions to make long-acting GLP-1/GIP-like proteins. In mice, one dose of the pLincretins construct produced detectable incretins for up to 70 days. In a head-to-head comparison, Wistar says mice given the DNA construct maintained metabolic…